Saturday, July 30, 2011

Acute Leukemia - Definition, Causes, Symptoms and treatment

Leukemia is a malignant disease (cancer) of the bone marrow and blood. It is characterized by the uncontrolled accumulation of blood cells. In Aml, the bone marrow makes many unformed cells called blasts. Aml starts with a turn to a particular cell in the bone marrow. With Aml, the leukemic cells are often referred. To as blast cells. Acute lymphocytic leukemia (All) is a fast-growing cancer in which the body produces a large estimate of immature white blood cells (lymphocytes). Aml is the most base acute leukemia affecting, and its incidence increases with age. Acute leukemia is a rapidly progressing disease that results in the accumulation of immature, functionless cells in the marrow and blood. In acute leukemia, cancerous cells multiply speedily and replace normal cells. Cancerous cells take over normal parts of bone marrow, causing bone marrow failure. A someone with All is more likely to bleed and have infections because there are fewer normal blood cells. Several congenital conditions may growth the risk of leukemia; the most base is probably Down syndrome, which is connected with a 10- to 18-fold growth in the risk of Aml.

Leukemia is divided into four categories: myelogenous or lymphocytic, each of which can be acute or chronic. Aml is more base in men than in women. Acute myelogenous leukemia is the most base form of leukemia. The incompatibility is even more apparent in older patients. Leukemia is one of the top 15 most oftentimes occuring cancers in minority groups. Leukemia incidence is highest among whites and bottom among American Indians and Alaskan natives. Signs of Aml are often non-specific, and may be similar to those of influenza or other base illnesses. Some generalized symptoms comprise fever, fatigue, weight loss or loss of appetite, shortness of breath with exertion, anemia, easy bruising or bleeding, petechiae (flat, pin-head sized spots under the skin caused by bleeding), bone pain and joint pain and persistent or frequent infections.This is likely because myelodysplastic syndromes (Mdss) are more base in men, and industrialized Mds oftentimes evolves into Aml. More than 11,900 new cases occur in the United States each year, mostly in older. The midpoint age of a someone with Aml is 65 years.

What Is Leukemia

Most of the approved rehabilitation for All uses chemotherapy.Chemotherapy is the preliminary rehabilitation of choice. Stem cell transplantation is used instead of consolidative chemotherapy. Radiation therapy is used on painful bony areas, in high disease burdens, or as part of the preparations for a bone marrow transplant (total body irradiation). Stem cell transplant. Stem cell transplant is also used for consolidation therapy. It's similar to bone marrow transplant except the stem cells are collected from circulating blood (peripheral blood). Induction therapy for children with Aml starts with two or three drugs. Stronger rehabilitation is needed after a child with Aml is in remission. This is called arduous consolidation therapy. It is given because ordinarily some Aml cells remain after induction therapy. Allogeneic stem cell transplant can be a high-risk procedure. For this reason, it may not be a good rehabilitation for some Aml patients. Bone marrow or cord blood transplant (also called a Bmt) offers some patients the best opening for a long-term remission of their disease.

Acute Leukemia for rehabilitation Tips

1. Chemotherapy -- drugs that destroy cancer cells or stop them from growing.

2. Bone marrow or cord blood transplant (also called a Bmt) offers some patients the best opening for a long-term remission of their disease.

3. Gemtuzumab ozogamicin (Mylotarg) and Monoclonal antibodies are proteins designed to attach to leukemia cells and help the immune principles destroy them.

4. Biological therapy attempts to stimulate or restore the quality of your child's immune principles to fight cancer.

5. Avoiding smoking, exposure to toxic chemicals, and exposure to radiation may help forestall some cases of leukemia.

6. Gemtuzumab ozogamicin is a monoclonal antibody against Cd33 (a molecule gift on most Aml cells but not on normal stem cells) conjugated to calicheamicin (a potent chemotherapy molecule).

7. Stem cell transplantation (Sct) is a rehabilitation that permits the use of doses of chemotherapy and radiation therapy high enough to destroy the patient's bone marrow.

Acute Leukemia - Definition, Causes, Symptoms and treatment

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